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Dr. Jeffrey Smiley
(on leave)
Current contact address:
email: j_smiley@acs.org
phone: 202-872-6093
fax: 202-872-6319 |
B.A.: Chemistry, Eastern Kentucky
University, 1982
Ph.D.: Biochemistry, University of North
Carolina at Chapel
Hill, 1991
Post-doctoral: Pennsylvania State
Uinversity, 1992-1995
Research Interests:
Mechanistic studies on decarboxylase enzymes
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Dr. Smiley is on professional leave for the 2006-07 academic year at
The American
Chemical Society Petroleum Research Fund. He is Program Officer
for PRF Grant Proposals within Committees 1 and 4, covering enzyme
chemistry,
organic chemistry, "green chemistry," and other subjects (see www.acsprf.org). He has
also been invited to serve on a National Institutes of Health review
panel that will consider grant applications for support from the
Minority
Biomedical Research Support (MBRS) Program. The MBRS Program,
funded by
the National Institute of General Medical Sciences, provides research
funding
to faculty members at minority-serving institutions.
Current address:
Jeffrey A. Smiley, Ph.D., Program Officer
Petroleum Research Fund, American Chemical Society
1155 Sixteenth Street, NW
Washington, DC 20036
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Recent
Publications:
"Genes of the thymidine salvage pathway: Thymine-7-hydroxylase from a
Rhodotorula glutinis cDNA library and iso-orotate decarboxylase from
Neurospora crassa," Smiley, J. A.; Kundracik, M.; Landfried, D. A.;
Barnes, V. R.; Axhemi, A. A. Biochimica
et Biophysica Acta 2005,
1723, 256-264.
"A guided inquiry
experiment for the measurement of
activation energies in the biophysical chemistry laboratory.
Decarboxylation of pyrrole-2-carboxylate," Hutchinson, K. M.; Bretz, S.
L.; Mettee, H. D.; Smiley, J. A. Biochemistry
and Molecular Biology Education 2005,
33, 123-127.
"A novel enzyme complex
of orotate
phosphoribosyltransferase and orotidine 5'-monophosphate decarboxylase
in human malaria parasite Plasmodium falciparum: Physical Association,
Kinetics, and Inhibition Characterization," Krungkrai, S. R.;
DelFraino, B. J.; Smiley, J. A.; Prapunwattana, P.; Mitamura, T.;
Horii, T.; Krungkrai, J. Biochemistry
2005, 44, 1643-1652.
"Survey of enzymological
data on ODCase," Smiley, J.
A. Topics in Current Chemistry
2004, 238, 63-78.
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