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    STaRBURSTT @ YSU Logo
    Seminar Coordinator: Dr. Allen D. Hunter

    Professor of Chemistry & Director of the STaRBURSTT CyberInstrumentation Consortia (at YSU & Nationally) *

    * STaRBURSTT is one of the many innovative approaches we use to give exceptional hands on education to our undergraduate and MS students.

    Upcoming Seminar


    For a Listing of Upcoming Seminars & Other Scheduled Activities see the STaRBURSTT@YSU Calendar:
    STaRBURSTT Calendar

    3:15 on Fri. May 5th for our   25th and Final Seminar for  2005-2006
    Dr. Megan Spence
    Photo of Megan Spence

    University of Pittsburgh
     
    Department of Chemistry

     

    “Structure and Dynamics of Peripheral Membrane Proteins and their Lipid Membrane Environment Observed with Solid-State NMR”






        We are interested in extending the use of solid-state NMR to  determining the structure of membrane-associated proteins.  Solid- state NMR has a unique ability to determine structures of membrane  proteins in native membrane environments, but is still in its infancy  compared to the sophistication of solution-state NMR techniques.  In  earlier work, we have examined the membrane-associated opioid,  leucine enkephalin (lenk), in which the order parameter is 0.1 (where  1 is fully crystalline and 0 is fully isotropic), requiring a  combination of solution-state and solid-state NMR techniques.  We are  also beginning work on membrane associated tarantula toxin, examining  the mechanism by which it inhibits mechanosensitive ion channels.


                                    

    Directions to YSU & Chemistry


    This Departmental Seminar Program is Associated with Three YSU Classes.
    Chemistry 3790: Undergraduate Seminar.
    Chemistry 6981: Seminar I (1st Year MS Students).
    Chemistry 6982: Seminar II (2nd Year MS Students).

    YSU Chemistry MS Graduate Students in 2005-2006
    Excellent Recruiting Targets!




    AdamCox

    AnithaMuttavarapu


    BhargaviVemulapalli

    DanielleJack

    Abdul-Basit Alhassan
    Adam Cox
    Anitha Muttavarapu
    Bhargavi Vemulapalli
    Danielle Jack

    DarylMains


    DebbieSmith


    ErinTreece


    JazerieWilliams


    JuliaSacui

    Daryl Mains
    Debbie Smith
    Erin Treece Jazerie Williams Julia Sacui

    LemuelCarlisle

    ManishDhawan

    MikeStrozewski




    MonicaVicarel


    NeelimaDobbala

    Lemuel Carlisle
    Manish Dhawan
    Mike Strozewski
    Monica Vicarel
    Neelima Dobbala

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    RyanConway

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    Rachel Kusnic Ragini Kankanala Ramnath Kallamadi Ryan Conway Sara Duncan

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    Sowmya Pabba Sridevi Ravulaparti Susmita Kapavarapu Umakanth Potula Uma Thatipally


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    2005-6 Seminar Schedule

    Dates
    (linked to Speaker Notices &
    Announcements)

    Speaker (linked to their YSU departmental and individual home page(s)), YSU Chemistry Department

    Presentation Title

    {Presentation Materials}

    #1 - September 23rd

    Seminar 1a: Peter Norris (Peter's Home Page)
    “Synthesis of Aminosugars,”

    Seminar 1b: Mike Serra
    “Metal Catalyzed Oxidation of Proteins,”       

    Seminar 1c: Larry Curtin (Larry's Home Page)
    “Ferrocene Containing Polymers and C60 Adducts”

    #2 - September 30th

    Seminar 2a: Howard Mettee
    “There's a Model in Your Future,”

    Seminar 2b: Sherri Lovelace Cameron  (Sherri's Home Page)
    “Organometallic Polymers,”

    Seminar 2c: Jeff Smiley
    “A Confused Enzyme: A Decarboxylase That Thinks its a Hydrolase”

    #3 - October 7th

    Seminar 3a: Tom Kim (Tom Kim's Home Page)
    “Proteomics”

    Seminar 3b: Jim Mike
    “Adventures in Separation Science”

    #4 - October 14th

    Seminar 4a: Tim Wagner (Tim's Home Page)
    “Inorganic Nitride Fluorides,”

    Seminar 4b: John Jackson (John's Home Page)
    “Synthesis & Reactions of Bis(2,2,2-trifluoroethyl)phosphinoalkynes,”

    Seminar 4c: Daryl Mincey (Daryl's Home Page)
    “Forensic Analytical Chemistry”

    #5 - October 21st

    Seminar 5a: Allen Hunter (Allen's Home Page)
    “Remote Instrumentation and the STaRBURSTT CyberInstrumentation Consortium”

    {Presentation Materials: PowerPoint.ppt, Adobe.pdf}

    Seminar 5b: Brian Leskiw
    “A “Physical” View of Mass Spectrometry”

    YSU Sabbatical & FIL Talks 2005-6

    #26 - Allen Hunter
    “Adventures with Organometallic NanoMaterials”

    #27 - Peter Norris
    “Synthesis of Amino Sugars”

    #28 - Mike Serra
    “The Use of Mass Spectrometry to Determine Sites of Oxidation”

    6981 Seminar I Spring 2006

    Ryan Conway - “???????”
    Glen Cox - “???????”
    Daryl Mains - “???????”
    Erin Treece - “???????”

    6982 Seminar II Fall 2005

    Neilima Dobbala - “???????”

    6982 Seminar II Spring 2006

    Vanessa Smiley - Tuesday May 2nd, 2006
    “
    Investigation into Two Mechanisms of Unusual Decarboxylases: a-Amino-β-Carboxymuconate e-Semialdehyde Decarboxylase and Orotidine 5’-Monophosphate Decarboxylase
    ”

    Debbie  Smith

    “???????”
    3790 Undergrad. Seminar Fall 2005 Lew Spirtos - "Anabolic Steroids" - November 30th, 2005
    {Presentation Materials: PowerPoint.ppt, Adobe.pdf}
    William (Bill) Karnofel - "Synthesis of Oxides and Pseudo-Oxides" - November 30th, 2005
    {Presentation Materials: PowerPoint.ppt, Adobe.pdf}

    3790 Undergrad. Seminar Spring 2006

    Khoa Dao - “???????”

     

     

    Seminar Dates


    Speaker (linked to their home page), Home Institution & Department (linked to thier home pages)
    "Presentation Title" (linked to speaker Notices & Abstracts as linked .pdf files)
    {Presentation Materials} 

      #6 - October 28th, 2005

    Rob Cicchillo, (YSU Alumni & graduating PhD student with S. J. Booker) Pennsylvania State University Department of Biochemistry and Molecular Biology.

    “Biochemical, Biophysical, and Mechanistic Investigations of Lipoyl Synthase from Escherichia coli: A Member of the “Radical SAM” Family of Enzymes”


    {Presentation Materials: Adobe.pdf}

    #7 - November 4th, 2005

    Ron Woodard Department of Medical Chemistry University of Michigan

    Ron Woodard, University of Michigan - Ann Arbor Department of Medicinal Chemistry

    “Mining New Microbial Pathways: Identification and Target Validation”

    #8 - November 18th, 2005

    Chris Hadad Department of Chemistry Ohio State University

    Chris Hadad, Ohio State University Department of Chemistry

    “Reactive Oxygen Species in Chemistry: Experiment and Theory”


    {Presentation Materials: Adobe.pdf}

    #9 - December 2nd, 2005

    Cora Lind University of Toledo Department of Chemistry

    Cora Lind, University of Toledo Department of Chemistry

    “Shrinking from the Heat: Negative Thermal Expansion Materials”


    {Presentation Materials: PowerPoint.ppt, Adobe.pdf}

    #10 January 20th, 2006

    Arthur Suits Department of Chemistry Wayne State University

    Arthur Suits, Wayne State University Department of Chemistry

    “Lost in Configuration Space: Probing Novel Reaction Mechanisms with High Resolution Imaging”

    Lead Paper(s): 
    (LP1)  Townsend, D.; Li, W.; Lee, S. K.; Gross, R. L.; Suits, A. G.: "Universal and State-Resolved Imaging of Chemical Dynamics," J. Phys. Chem. A., 2005, 109 (Oct. 6th), 8661-8674.

    #11 - February 14th, 2006

    Tuesday
    Photo of Joe Grabowski

    Joe Grabowski, University of Pittsburgh Department of Chemistry

    “What is the Demand for Undergraduate Research? A Multi-Year Study of the NSF REU Chemistry Applicant Pool”
     
    Lead Paper(s): 
    (LP1)  Coon, D. M.; Duran, R. S.; Haines, D. R.; Grabowski, J. J.:
    "What is the Demand for Undergraduate Research? A Multi-year Study of the NSF REU Chemistry Applicant Pool," J. Chem. Ed., 2005, (October), submitted for publication.
    (LP2)  http://www.chem.pitt.edu/ugrad/reu/efficacy.htm
    (LP3)  http://www.as.ysu.edu/~adhunter/RFPs/REU.nsf05592.pdf

    #12 - January 27th, 2006

    Photo of Danith Ly

    Danith Ly, Carnegie Mellon University  Department of Chemistry

    “New Research Opportunities at the Chemistry-Biology Interface”

     
    Lead Paper(s):
    (LP1)  Zhou, P.; Wang, M.; Du, L.; Fisher, G. W.; Waggoner, A.; Ly, D. H.: "Novel Binding and Efficient Cellular Uptake of Guanidine-Based Peptide Nucleic Acids (GPNA)," J. Am. Chem. Soc., 2003, 125, 6878-6879.
    (LP2)  Dragulescu-Andrasi, A.; Zhou, P.; He, G.; Ly, D. H.: "Cell-Permeable GPNA with Appropriate Backbon Stereochemistry and Spacing Binds Sequence-Specifically to RNA," Chem. Comm., 2005, 244-246.

    #13 - February 3rd, 2006

    Photo of Aprill Stalcup

    Apryll Stalcup, University Cincinnati Department of Chemistry

     “Ionic Liquids in Separations”
     
    Lead Paper(s):
    (LP1)  Stalcup, A. M.; Cabovska, B.: "Ionic Liquids in Chromatography and Capillary Electrophoresis," J. Liquid Chrom. & Related Technologies," 2004, 27, 1443-1459.
    (LP2)  Sun, Y.; Cabovska, B.; Evans, C. E.; Ridgway, T. H.; Stalcup, A. M.: "Rentention Characteristics of a New Butylimidazolium-Based Stationary Phase," Anal. Bioanal. Chem., 2005, 382, 728-734.
    (LP3)  Cabovska, B.; Kreishman, G. P.; Wassell, D. F.; Stalcup, A. M.: "Capillary Electrophoretic and Nuclear Magnetic Resonance Studies of Interactions Between Halophenols and IOnic Liquid or Tetraalkylammonium Cations," J. Chrom. A., 2003, 1007, 179-187.
    (LP4)  Yanes, E. G.; Gratz, S. R.; Baldwin, M. J.; Robison, S. E.; Stalcup, A. M.: "Capillary Electrophoretic Application of 1-Alkyl-3Methylimidazolium-Based Ionic Liquids," Anal. Chem., 2001, 73, 3838-3844.

    #14 - February 10th, 2006

    Photo of Tony Berdis

    Tony Berdis, Case Western Reserve University,  Department of Pharmacology

    “Non-Natural Nucleotides as Chemotherapeutic Agents”

     

    Lead Paper(s): 
    (LP1)  Allan, J. M.; Travis, L. B.: "Mechanisms of Therapy-Related Carcinogenesis," Nature Reviews - Cancer, 2005, 5, 943-955.

    (LP2)  Zhang, X.; Lee, I.; Berdis, A. J.: "A Potential Chemotherapeutic Stratey for the Selective Inhibition of Promutagenic DNA Synthesis by Nonnatural Nucleotides," Biochemistry, 2005, 44, 13111-13121.
    (LP3)  Henry, A. S.; Romesberg, F. E.: "Beyond A, C, G and T: Augmenting Nature's Alphabet," Current Opionion in Chem. Bio., 2003, 7, 727-733.

    #15 - February 17th, 2006

    Jared Anderson Photo

    Jared Anderson, University of Toledo  Department of Chemistry

    “Room Temperature Ionic Liquids: Applications in Analytical Chemistry”


    Lead Paper (s):
    (LP1)  Welton, T.: "Room Temperature Ionic Liquids. Solvents for Synthesis and Catalysis,"  Chem. Revs., 1999, 99, 2071-2083.
    (LP2) 
    Anderson, J.L.; Armstrong, D.W.: “Immobilized Ionic Liquids as High Temperature/High Selectivity/High Temperature Gas Chromatography Stationary Phases,” Anal. Chem., 2005, 77, 6453-6462.

    #16 - February 24th, 2006

    Photo of James Kiddle

    James Kiddle, Western Michigan University Department of Chemistry

    “Chiral Multipurpose Organophosphorus Compounds for Asymmetric Synthesis”
     
    Lead Paper(s): 

    (LP1)  Rein, T.; Pedersen, T. M.:  "Asymmetric Wittig Type Reactions," Synthesis, 2002,  579-594.

    (LP2)  Ager, D. J.; Prakash, I.; Schaad, D. R.: "1,2-Amino Alcohols and Their Heterocyclic Derivatives as Chiral Auxiliaries in Asymmetric Synthesis," Chemical Reviews, 1996, 96,  835-75.
    (LP3)  Lidstrom, P.; Tierney, J.; Wathey, B.; Westman, J.: "Microwave Assisted Organic Synthesis: A Review," Tetrahedron,  2001,  57,  9225-9283.

    #17 - March 3rd, 2006

    Photo of Peter Rinaldi

    Peter Rinaldi, University of Akron Department of Chemistry

    “Non-Biological Applications  of 3D-NMR Experments”
     
    Lead Paper(s):

    (LP1)  Rinaldi, P. L.: "Three-deminsional solution NMR Spectroscopy of Complex Structures and Mixtures," The Analyst, 2004, 129, 687-699.

    #18 - March 10th, 2006

    Photo of Irene Lee

    Irene Lee, Case Western Reserve University Department of Chemistry

    “Development of anti-bacterial agent through mechanistic enzymology of Lon Protease”
     
    Lead Paper(s):

    (LP1)  Schreiber, S. L.: "Target-Oriented and Diversity-Oriented Organic Synthesis in Drug Discovery," Science, 2000, 287, 1964-1969.

    (LP2)  MacCoss, M.; Baillei, T. A.: "Organic Chemistry in Drug Discovery," Science, 2004, 303, 1810-1813.

    #19 - March 24th, 2006

    Photo of Mike Freitas

    Mike Freitas, Ohio State University Department of Chemistry

    “Identification of Histone Post-Translational Modifications”

     
    Lead Paper(s):
    (LP1) 

    #20 - March 31st, 2006

    Photo of Tim Mueser

    Tim Mueser, University of Toledo Department of Chemistry

    “X-Ray Crystallographic Studies of DNA Replication”
     

    Lead Paper(s):
    (LP1)  Mueser, T. C.; Nossal, N. G.; Hyde, C. C.: "Structure of Bacteriophage T4 RNase H, a 5' to 3' Exonuclease with Sequence Similarity to the RAD2 Family of Eukaryotic Repair and Replication Proteins," Cell, 1996, 85, 1101-1112.
    (LP2)  Mueser, T. C.; Jones, C. E.; Nossal, N. G.; Hyde, C. C.: "Bacteriophage T4 Gene 59 Helicase Assembly Protein Binds Replication Fork DNA.  The 1.45A Resolution Crystal Structure Reveals a Novel Alpha Helical Two-Domain Fold," J. Molec. Biology, 2000, 296, 597-612.

    #21 - April 7th, 2006

    Photo of Laura Voss

    Laura Voss (A senior member of Heather Allen's Research Group), Ohio State University Department of Chemistry

    “Surfaces impacting climate change:  The role of fatty acid monolayers in tropospheric chemistry”

    Lead Paper(s):
    (LP1) 

    #22 - April 14th, 2006
    Postponed Until Fall 2006

    Photo of Dr. Mike Sponsler

    Michael Sponsler, Syracuse University Department of Chemistry

    “Stoichiometric Olefin Metathesis as a Connection Method for Molecular Electronics”


    Lead Paper(s):
    (LP1) 
    Williams, J. E.; Harner, M. J.; Sponsler, M. B.: "Ruthenium Alkylidenes: Fast Initiators for Olefin Metathesis,"   Organometallics, 2005, 24, 2013-2015.
    (LP2) 
    Schuehler, D. E.; Williams, J. E.; Sponsler, M. B.: "Polymerization of Acetylene with a Ruthenium Olefin Metathesis Catalyst," Macromolecules, 2004, 37, 6255-6257.
    (LP3) 
    Niu, X.; Gopal, L.; Masingale, M. P.; Braden, D. A.; Hudson, B. S.; Sponsler, M. B.: "Experimental and Theoretical Investigation of Z-E Alkene Isomerization in [(Cy3P)2Cl2Ru]2(µ-CHCH=CHCH) and Related Vinylalkylidenes," Organometallics, 2000, 19, 649-660.

    #23 - April 21st, 2006
    Postponed Until Fall 2006

    Photo of Christine Moravec

    Christine Moravec, Cleveland Clinic Department of  Molecular Cardiology


    “Reversing Human Heart Failure”


    Sponsored by the YSU American Chemical Society Student Affiliates Chapter

     
    Lead Paper(s):
    (LP1) 

    #24 - April 28th, 2006

    Photo of Pat Woodward

    Pat Woodward, Ohio State University Department of Chemistry

    “The NSF – Ohio REEL Project”